During an outpatient clinic follow-up appointment, a client with multiple sclerosis (MS)has lab tests completed. The results show elevated levels of aspartate aminotransferase (AST), serum glutamic-oxaloacetic transaminase (SGOT), alanine aminotransferase (ALT), serum glutamic-pyruvic transaminase (SGPT), and alkaline phosphatase (ALP). The nurse recognizes that these elevated enzyme levels are a potential adverse effect of which medications? Select all that apply.
A)Interferon beta-1a (Avonex)
B)Teriflunomide (Aubagio)
C)Glatiramer acetate (Copaxone)
D)Mitoxantrone (Novantrone)
E)Fingolimod (Gilenya)

Question

Quizplus · Accepted Answer

A)AST, SGOT, ALT, SGPT, and ALP are liver enzymes that are monitored to detect adverse responses to the medications interferon beta-1a (Avonex)and teriflunomide (Aubagio). Glatiramer acetate (Copaxone), mitoxantrone (Novantrone), and fingolimod (Gilenya)are used to treat MS but do not typically cause liver damage.
B)AST, SGOT, ALT, SGPT, and ALP are liver enzymes that are monitored to detect adverse responses to the medications interferon beta-1a (Avonex)and teriflunomide (Aubagio). Glatiramer acetate (Copaxone), mitoxantrone (Novantrone), and fingolimod (Gilenya)are used to treat MS but do not typically cause liver damage.
C)AST, SGOT, ALT, SGPT, and ALP are liver enzymes that are monitored to detect adverse responses to the medications interferon beta-1a (Avonex)and teriflunomide (Aubagio). Glatiramer acetate (Copaxone), mitoxantrone (Novantrone), and fingolimod (Gilenya)are used to treat MS but do not typically cause liver damage.
D)AST, SGOT, ALT, SGPT, and ALP are liver enzymes that are monitored to detect adverse responses to the medications interferon beta-1a (Avonex)and teriflunomide (Aubagio). Glatiramer acetate (Copaxone), mitoxantrone (Novantrone), and fingolimod (Gilenya)are used to treat MS but do not typically cause liver damage.
E)AST, SGOT, ALT, SGPT, and ALP are liver enzymes that are monitored to detect adverse responses to the medications interferon beta-1a (Avonex)and teriflunomide (Aubagio). Glatiramer acetate (Copaxone), mitoxantrone (Novantrone), and fingolimod (Gilenya)are used to treat MS but do not typically cause liver damage.

During an Outpatient Clinic Follow-Up Appointment, a Client with Multiple