CASE HISTORY In Wichita,Kansas,a 20-Year-Old College Student Named Lillian Visited the College
CASE HISTORY
In Wichita,Kansas,a 20-year-old college student named Lillian visited the college health practitioner for a routine gynecological exam.Lillian's periods had been regular,but she recently noted some spotting between periods.Her last menstrual period was four weeks prior.The practitioner asked Lillian whether she was sexually active.Lillian reported two male partners within the past six months.She reported no vaginal discharge,dyspareunia (painful intercourse) ,genital lesions,or sores.Her breast,thyroid,and abdominal exam were within normal limits,as were her vital signs-blood pressure: 118/68,pulse: 74,respiration: 18,temperature: 37.1°C (98.6°F) .
The genital exam revealed normal vulva and vagina.The practitioner found no cervical motion pain and no uterine or adnexal tenderness (areas that include and surround the fallopian tubes and ovaries) .But Lillian's cervix appeared inflamed and bled easily,with a purulent discharge coming from the cervical os (opening) .
The practitioner performed nucleic acid amplification tests (NAATs) for Chlamydia trachomatis and Neisseria gonorrhoeae.Within a day,the NAAT results were positive for Chlamydia and negative for N.gonorrhoeae.Wet-mount microscopy revealed no pathogens but many WBCs (white blood cells) .The diagnosis was confirmed as chlamydia infection,an infection reportable to the Centers for Disease Control and Prevention (CDC) .
The practitioner prescribed doxycycline to clear up the infection.To curtail transmission,the practitioner asked Lillian to identify all her sexual partners for partner notification.Lillian recalled a third partner seven months earlier.The practitioner also recommended use of condoms to decrease further infections.
Doxycycline is an antibiotic that binds to the bacterial ribosome.How does this antibiotic interfere with the creating of proteins in bacterial cells?
A) Binding to the ribosome prevents DNA strands from being separated properly, preventing transcription.
B) Binding to the ribosome prevents mRNA strands from being properly assembled from single-stranded DNA templates.
C) Binding to the ribosome prevents mRNA from being properly read and translated into an amino acid sequence.
D) Binding to the ribosome prevents completed proteins from being exported to the cell surface.
Correct Answer:
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