Individuals with bare lymphocyte syndrome lack MHC II proteins.Which of the following could still occur in an individual lacking MHC II proteins?

Question

Quizplus · Accepted Answer

MHC II proteins are needed for presentation of antigens to helper T cells and subsequent activation of B cells for class switching and production of IgG, IgA, and IgE antibodies. However, B cells can still produce IgM antibodies in the absence of MHC II proteins, as IgM production does not require T cell help. Therefore, option B is the best choice. Options A, C, and D are incorrect as they all require T cell activation which in turn relies on MHC II presentation of antigens.

Individuals with Bare Lymphocyte Syndrome Lack MHC II Proteins