Type II hypersensitivities differ from type III sensitivities in that only type II involves

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Type II hypersensitivities involve antibodies that bind to surface antigens on target cells or tissues, leading to destruction of the cells through complement activation or antibody-dependent cell-mediated cytotoxicity (ADCC). In contrast, type III hypersensitivities involve immune complex formation with soluble antigens, which can deposit in various tissues and cause localized inflammation and tissue damage. Histamine is not directly involved in either type II or type III hypersensitivities.

Type II Hypersensitivities Differ from Type III Sensitivities in That