How Do Rickettsioses,such as Rocky Mountain Spotted Fever,cause Systemic Symptoms

How do rickettsioses,such as Rocky Mountain spotted fever,cause systemic symptoms?

A) Rickettsia species are obligate intracellular bacteria that infect endothelial cells throughout the body.
B) Rickettsia species are phagocytized by macrophages and travel throughout the blood within macrophages.
C) Rickettsia species infect lymphocytes and use the lymphatic system to move throughout the body.
D) Rickettsia species infect fibroblasts within connective tissues and use the reticuloendothelial system to move throughout the body.