Given the following data for substance X, how much of substance X is filtered, reabsorbed, and excreted GFR = 125 mL/min; Tm = 125 mg/min at a plasma concentration of 200 mg/100 mL
A)125 mg/min filtered, 125 mg/min reabsorbed, 0 mg/min excreted
B)200 mg/min filtered, 125 mg/min reabsorbed, 75 mg/min excreted
C)250 mg/min filtered, 125 mg/min reabsorbed, 125 mg/min excreted
D)250 mg/min filtered, 200 mg/min reabsorbed, 50 mg/min excreted

Question

Quizplus · Accepted Answer

First, calculate the amount of substance X filtered per minute: (200 mg/100 mL) * (125 mL/min) = 250 mg/min. Since the Tm (maximum transport rate for reabsorption) is 125 mg/min, this is the amount reabsorbed. The difference between filtered and reabsorbed amounts (250 mg/min - 125 mg/min) gives the excreted amount, which is 125 mg/min.

Given the Following Data for Substance X, How Much of Substance