Which of the following would be an appropriate response to an Institutional Animal Care and Use Committee's (IACUC's)request for more refinement in a study application to use animals in research?
A) The researcher found an alternative study procedure that caused less pain and distress for study animals.
B) The researcher decided to use fewer animals in the study.
C) The researcher found a computer simulation that could be used instead.
D) The researcher added new study objectives to increase the scientific value of the study.

Question

Quizplus · Accepted Answer

Refinement refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain and distress. Finding an alternative procedure that causes less pain and distress directly aligns with the principle of refinement.

Which of the Following Would Be an Appropriate Response to an Institutional