A drug that is catabolized by enzymes into multiple metabolites before reaching its site of action likely:
A) functioned as a prodrug.
B) underwent Phase II biotransformation.
C) acted in a conjugation reaction.
D) underwent first-pass metabolism.

Question

Quizplus · Accepted Answer

First-pass metabolism refers to the process where a drug is metabolized at a specific location in the body that results in a reduced concentration of the active drug upon reaching its site of action. This often occurs in the liver, where enzymes break down the drug into multiple metabolites before it can exert its effects elsewhere in the body.

A Drug That Is Catabolized by Enzymes into Multiple Metabolites