Which of the following approaches might a pharmacologist take in order to increase concentrations of a neurotransmitter in the synaptic cleft?

Question

Quizplus · Accepted Answer

Blocking membrane transporters would prevent the reuptake of the neurotransmitter from the synaptic cleft back into the presynaptic neuron, leading to an increase in concentration in the synaptic cleft. Option B is incorrect as increasing catabolic enzyme activity would break down the neurotransmitter and decrease its concentration. Option C is incorrect as blocking calcium channels would reduce the influx of calcium into the presynaptic neuron, which is necessary for exocytosis of neurotransmitters into the synaptic cleft. Option D is incorrect as blocking postsynaptic receptors would not increase the concentration of the neurotransmitter in the synaptic cleft.

Which of the Following Approaches Might a Pharmacologist Take in Order