A ternary receptor model suggests that:
A) only ligands with a high affinity for a receptor can activate a receptor.
B) a G-protein can prevent a ligand from binding to a receptor.
C) receptor actions depend on an interaction between a ligand, receptor, and G-protein.
D) receptor efficacy only pertains to metabotropic receptors.

Question

Quizplus · Accepted Answer

A ternary receptor model proposes that receptor actions depend on the interaction between the ligand, receptor, and G-protein. In this model, the ligand typically binds to the receptor and activates it, while the G-protein can modulate this activation by enhancing or inhibiting the receptor's intracellular signaling. The model assumes that receptor activation requires a heterotrimeric G protein, which acts as a molecular switch to regulate the receptor's activity. Therefore, it suggests that the efficacy of a receptor can be influenced by the interaction between the ligand, receptor, and G protein.

A Ternary Receptor Model Suggests That