Finding that chronic administration of a psychostimulant reduced dopamine receptors in the brain would be an example of:
A) pharmacokinetic tolerance.
B) pharmacodynamic tolerance.
C) sensitization.
D) conditioned tolerance.

Question

Quizplus · Accepted Answer

Pharmacodynamic tolerance refers to the changes that occur in the brain in response to chronic drug use, such as changes in receptor sensitivity or number. In this case, chronic administration of a psychostimulant has led to a reduction in dopamine receptors, which is an example of pharmacodynamic tolerance.

Finding That Chronic Administration of a Psychostimulant Reduced Dopamine Receptors