Methylphenidate increases dopamine levels in the synaptic cleft by:

Question

Quizplus · Accepted Answer

Methylphenidate is a dopamine reuptake inhibitor, meaning it inhibits the membrane transporters responsible for the reuptake of dopamine from the synaptic cleft into the presynaptic neuron. This leads to an increase in dopamine levels in the synaptic cleft, which can activate dopamine receptors and increase dopamine signaling. Therefore, choice C (inhibiting dopamine membrane transporters) is the best choice. The other choices (increasing dopamine synthesis, activating dopamine receptors, and inhibiting monoamine oxidase) are not mechanisms of action for methylphenidate.

Methylphenidate Increases Dopamine Levels in the Synaptic Cleft By