Desensitization of the nicotinic receptor sooner after an agonist binds to the receptor means that:
A) the ion flow through the open channel is reversed.
B) G-proteins enter an inactive state.
C) the nicotinic receptor ion channel closes.
D) the agonist is repelled from the receptor binding site.

Question

Quizplus · Accepted Answer

Desensitization of the nicotinic receptor means that the receptor ion channel closes, preventing further ion flow through the open channel. This occurs when the receptor becomes unresponsive or less responsive to the agonist binding to it. The other options do not accurately describe desensitization of the nicotinic receptor.

Desensitization of the Nicotinic Receptor Sooner After an Agonist Binds