Taking an antidepressant drug that is catabolized by the same enzyme for caffeine would:
A) diminish the pharmacological effects of caffeine.
B) reduce absorption of caffeine.
C) shorten the elimination rate for caffeine.
D) prolong the effects of caffeine.

Question

Quizplus · Accepted Answer

If the antidepressant drug is catabolized by the same enzyme as caffeine, it may compete with caffeine for the enzyme's attention, thereby reducing its rate of metabolism, which could lead to prolonged effects of caffeine. This is particularly true if the antidepressant drug is a potent inhibitor of the enzyme responsible for metabolizing caffeine, known as CYP1A2. As a result, caffeine may remain in the bloodstream longer, causing an extended pharmacological effect.

Taking an Antidepressant Drug That Is Catabolized by the Same