Which of the following mechanisms can produce reinforcing effects?
A) Inhibiting dopamine release in the nucleus accumbens.
B) Blocking GABAA receptors in the ventral tegmental area.
C) Activating GABAA receptors in the nucleus accumbens.
D) Increasing GABA release from neurons terminating in the ventral tegmental area.

Question

Quizplus · Accepted Answer

Activating GABAA receptors in the nucleus accumbens can produce reinforcing effects by enhancing the activity of the mesolimbic dopamine system, which is involved in reward and motivation. This can increase the release of dopamine in response to drugs or other rewarding stimuli, leading to a positive reinforcement of the behavior. Inhibiting dopamine release in the nucleus accumbens (A), blocking GABAA receptors in the ventral tegmental area (B), and increasing GABA release from neurons terminating in the ventral tegmental area (D) can all have opposite effects and decrease the reinforcing effects of drugs and other rewards.

Which of the Following Mechanisms Can Produce Reinforcing Effects