In a drug discrimination procedure using GHB as a training drug,why might the GABAB receptor agonist baclofen produce full substitution?
A) GABAB receptors produce inhibitory effects similar to positive modulation of GABAA receptors.
B) GABAB receptors interact with GHB receptors.
C) GHB is an agonist for GABAB receptors.
D) baclofen is also an agonist for GHB receptors.

Question

Quizplus · Accepted Answer

GHB acts as an agonist at GABAB receptors, which explains why baclofen, a GABAB receptor agonist, would produce full substitution in a drug discrimination procedure using GHB as the training drug.

In a Drug Discrimination Procedure Using GHB as a Training