Giving an opioid antagonist to an opioid dependent user will produce withdrawal symptoms.

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Opioid antagonists, such as naloxone or naltrexone, can precipitate withdrawal symptoms in individuals who are physically dependent on opioids. This is because these medications block the activity of opioids, which can lead to a sudden and severe onset of withdrawal symptoms, including nausea, vomiting, diarrhea, body aches, and cravings. Therefore, opioid antagonists should only be used under medical supervision, and patients should be closely monitored for signs of withdrawal.

Giving an Opioid Antagonist to an Opioid Dependent User Will