A hypothesis for how to develop an atypical antipsychotic drug states that an antagonist for D₂ receptors that quickly separates from the receptor is called the…

Question

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The hypothesis described in the statement is known as the fast D₂-off hypothesis, which proposes that the ideal atypical antipsychotic drug should be a D₂ receptor antagonist that binds to the receptor tightly enough to exert therapeutic effects but quickly dissociates from it to minimize adverse effects. The other options (B, C, D) refer to different hypotheses related to the pharmacology of antipsychotic drugs but are not specific to the development of atypical antipsychotics.

A Hypothesis for How to Develop an Atypical Antipsychotic Drug