TAT is a codon for the amino acid tyrosine (Tyr) .If a mutation changes TAT to TAA,what kind of mutation has occurred?

Question

TAT is a codon for the amino acid tyrosine (Tyr).If a mutation changes TAT to TAA,what kind of mutation has occurred?

Quizplus · Accepted Answer

The change from TAT to TAA results in a premature stop codon, which terminates the translation of the protein, leading to a truncated and likely non-functional peptide. This type of mutation, where a sense codon is replaced by a premature stop codon, is called a nonsense mutation. A frameshift mutation would result from an insertion or deletion of one or more nucleotides, causing a shift in the reading frame. A missense mutation would result from a change in one nucleotide, leading to a different amino acid being incorporated into the protein. A silent mutation would result from a change in one nucleotide, but the same amino acid would still be incorporated into the protein, so the mutation would not have any functional consequence.

TAT Is a Codon for the Amino Acid Tyrosine (Tyr)