Which repair process leads to an abasic site as part of the repair pathway?

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Quizplus · Accepted Answer

Base excision repair involves the removal of damaged bases by specific glycosylases, which create an abasic (apurinic/apyrimidinic, or AP) site in the DNA. The AP site is then cleaved by AP endonuclease, and the resulting gap is filled in by polymerase and ligase enzymes, restoring the original sequence. Methyl mismatch repair involves recognition and removal of mismatched bases by MutS and MutL proteins. Recombination involves exchange of genetic information between homologous chromosomes or sites, often during meiosis. SOS (stimulon of repair) repair is a process that activates a set of DNA repair genes in response to extensive DNA damage, including damage that stalls replication forks.

Which Repair Process Leads to an Abasic Site as Part