Clonal expansion of B cells occurs when a(n)

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Clonal expansion occurs when a single B cell is activated by the binding of its receptor to a single epitope on an antigen. This results in the B cell dividing to produce a large number of identical copies, or clones, that are capable of producing antibodies against that specific antigen. Antigen-presenting cells and helper T cells play important roles in the activation and differentiation of B cells, but they do not bind directly to individual B cells to cause clonal expansion. Similarly, memory B cells are already activated and do not undergo clonal expansion upon encountering their specific antigen again.

Clonal Expansion of B Cells Occurs When A(n)