Which principle, bolstered by the Tenth Amendment, made it difficult for the federal government to address the issue of slavery prior to the Civil War?

Question

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The Tenth Amendment protects states' rights, which gave states the power to decide whether or not to allow slavery within their borders. As a result, the federal government did not have the authority to directly address the issue of slavery, as it was considered a states' issue. This made it difficult for the federal government to implement any national policies or laws related to slavery without overstepping its constitutional authority.

Which Principle, Bolstered by the Tenth Amendment, Made It Difficult