What is a consequence of plasma membrane damage to the mitochondria?
A)Enzymatic digestion halts DNA synthesis.
B)Influx of calcium ions halts ATP production.
C)Edema from an influx in sodium causes a reduction in ATP production.
D)Potassium shifts out of the mitochondria, which destroys the infrastructure.

Question

Quizplus · Accepted Answer

Calcium alterations are an important mechanism of cell injury and death. Cell membrane injury leads to calcium influx into the cell. An influx of calcium ions from the extracellular compartment activates multiple enzyme systems, resulting in cytoskeleton disruption, membrane damage, activation of inflammation, and eventually DNA degradation. Calcium ion accumulation in the mitochondria causes the mitochondria to swell, which is an occurrence that is associated with irreversible cellular injury. The injured mitochondria can no longer generate ATP, but they do continue to accumulate calcium ions. Mitochondrial consequences of cell membrane damage do not include enzymatic digestion, reduced ATP production due to edema, or infrastructure damage from potassium shifts.

What Is a Consequence of Plasma Membrane Damage to the Mitochondria