What is the role of fibroblasts during the reconstructive phase of wound healing?
A)Generate new capillaries from vascular endothelial cells around the wound.
B)Establish connections between neighboring cells and contract their fibers.
C)Synthesize and secrete collagen and the connective tissue proteins.
D)Provide enzymes that débride the wound bed of dead cells.

Question

Quizplus · Accepted Answer

Fibroblasts are the most important cells during the reconstructive phase of wound healing because they synthesize and secrete collagen and other connective tissue proteins. Macrophage-derived transforming growth factor-beta (TGF-ß) stimulates fibroblasts. Fibroblasts do not generate new capillaries, establish connections between neighboring cells, or provide enzymes to debride the wound bed.

What Is the Role of Fibroblasts During the Reconstructive Phase