What congenital malformation is commonly linked to acute leukemia in children?

Question

Quizplus · Accepted Answer

Trisomy 21 (Down syndrome) is the most common genetic defect linked to the development of acute leukemia. Children with Down syndrome have a 10- to 20-fold increased risk of developing acute lymphoblastic and myelogenous leukemia and a higher risk for developing acute megakaryocytic leukemia. No current research supports a link between Wilms tumor, retinoblastoma, or neuroblastoma and acute leukemia.

What Congenital Malformation Is Commonly Linked to Acute Leukemia in Children