Which endogenous opioid is located in the hypothalamus and pituitary and is a strong m-receptor agonist?
A)Enkephalins
B)Endorphins
C)Dynorphins
D)Endomorphins

Question

Quizplus · Accepted Answer

The synthesis and activity of b-endorphin is concentrated in the hypothalamus and the pituitary gland and act as strong m-receptor agonist. Enkephalins are the most prevalent of the natural opioids and bind to d opioid receptors. Enkephalins are concentrated in the hypothalamus, the PAG matter, the nucleus raphe magnus of the medulla, the dorsal horns of the spinal cord, but not the pituitary. Dynorphins are the most potent of the endogenous opioids binding strongly with k receptors to impede pain signals in the brain. They play a role in mood disorders and drug addiction and paradoxically in stimulating chronic pain. Endomorphins are dynorphins.

Which Endogenous Opioid Is Located in the Hypothalamus and Pituitary