The first major consideration on the clinical utility axis is external validity, which asks all of the following questions EXCEPT,

Question

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External validity concerns the generalizability of the research findings to real-world settings. Questions A, B, and D are directly related to external validity as they deal with the practical aspects of applying the intervention in a real-world context. Question C, asking if research has shown the treatment to be effective in different settings, actually pertains to the concept of internal validity, which is about the accuracy of the study's results.

The First Major Consideration on the Clinical Utility Axis Is