Frameshift mutations
A) cause a change in the reading frame of mRNA codons.
B) are usually caused by base analogs.
C) usually occur because of radiation exposure.
D) cause a single amino acid change in the polypeptide chain.
E) are usually the result of damage caused by free radicals.

Question

Quizplus · Accepted Answer

Frameshift mutations result from the insertion or deletion of nucleotides that alter the grouping of codons in the mRNA sequence, causing a shift in the reading frame. This often leads to a completely altered amino acid sequence downstream of the mutation site. Base analogs, radiation exposure, and free radicals can all cause mutations but are not specifically associated with frameshift mutations. Frameshift mutations do not typically result in a single amino acid change, but rather a significant alteration in the protein product.

Frameshift Mutations