The two major checkpoints in the cell cycle are the

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The two major checkpoints in the cell cycle are the G1/S and G2/M checkpoints. The G1/S checkpoint ensures that the cell has enough energy and nutrients to commence DNA synthesis and replication. The G2/M checkpoint makes sure that the cell has finished DNA replication and that the DNA is undamaged and ready for cell division. Prophase and metaphase are stages of mitosis and not major checkpoints. The interphase/M checkpoint is not a recognized checkpoint in the cell cycle.

The Two Major Checkpoints in the Cell Cycle Are the