What approach did Nancy Wexler take to identify a DNA marker associated with Huntington disease?
A) population-based pedigree and DNA analysis
B) DNA analysis of people from all over the world
C) gathering DNA from members of her family
D) DNA analysis of the entire population of Venezuela
E) concordance analysis between monozygotic and dizygotic twins

Question

Quizplus · Accepted Answer

Nancy Wexler used a population-based pedigree and DNA analysis to identify a DNA marker associated with Huntington disease. She studied a large population of individuals in Venezuela who shared a common ancestry and had a high prevalence of the disease. By analyzing the DNA of affected individuals and their relatives, she was able to identify the genetic marker associated with the disease.

What Approach Did Nancy Wexler Take to Identify a DNA