An 8 year old child was brought to his family physician because of fever,lethargy,and sudden weight gain.He had previously been well,except for a recent bout with "strep throat".Upon physical examination,severe peripheral oedema (grade 3+)was noted.Urinalysis disclosed increased amounts of protein and RBCs.A renal biopsy was performed,a representative section of which is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?

Question

Quizplus · Accepted Answer

The history of "strep throat" in a child with renal problems should immediately suggest the fairly common diagnosis of acute proliferative glomerulonephritis.Glomerular cellularity is markedly increased due to swelling and proliferation of endothelial and mesangial cells and infiltration by neutrophils (N).

An 8 Year Old Child Was Brought to His Family