While doing an autopsy of a brain, Dr. Howard shakes her head in disgust, saying, "This is just awful." When an assistant asks her what she sees, she says, "Deformed axons." What was the source of Dr. Howard's disgust?
A) neuritic plaques
B) neurotransmitters
C) free radical damage
D) neurofibrillary tangles

Question

Quizplus · Accepted Answer

Neurofibrillary tangles are a hallmark pathological feature of Alzheimer's disease and can cause neurodegeneration. Deformed axons are a result of the accumulation of hyperphosphorylated tau protein that makes up the neurofibrillary tangles, leading to a breakdown in communication between neurons. Dr. Howard's disgust is likely due to the severity of the tangle accumulation.

While Doing an Autopsy of a Brain, Dr