Familial Alzheimer's disease is linked to which one of the following causative genes?
A) ALS8
B) PSEN2
C) TMG6
D) APOE-e4

Question

Quizplus · Accepted Answer

Familial Alzheimer's disease is linked to mutations in three genes: APP, PSEN1, and PSEN2. The PSEN2 gene is one of the causative genes for familial Alzheimer's disease. ALS8 is a gene linked to familial ALS, TMG6 is not a known causative gene for any disease, and APOE-e4 is a risk factor for late-onset Alzheimer's disease but not familial Alzheimer's disease.

Familial Alzheimer's Disease Is Linked to Which One of the Following