The poly A tail found at the end of the picornavirus genome is created using the same mechanism as the poly A tails on host cell mRNAs.

Question

Quizplus · Accepted Answer

The poly A tail of picornavirus genomes is not synthesized using the same polyadenylation process as host cell mRNAs. Instead, it is generated through a mechanism involving the viral RNA-dependent RNA polymerase, which differs from the polyadenylation process used for cellular mRNAs.

The Poly a Tail Found at the End of the Picornavirus