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Binding of the Large T Antigen of SV40 to the Cellular

Question 5

Multiple Choice

Binding of the large T antigen of SV40 to the cellular protein pRb causes which of the following to occur?


A) Degradation of the cellular protein p53
B) Activation of the apoptosis pathway.
C) Replication of viral DNA
D) Dissociation of the transcription factor E2F.
E) Blocks progression through the cell cycle.

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