Which of the following must occur in nonpermissive cells which become transformed by the polyomavirus SV40?
A) The viral origin of replication must become inactivated.
B) Cellular DNA becomes packaged into virions.
C) The early viral genes become integrated into the host chromosome.
D) The Rb protein becomes bound to E2F.
E) The large T antigen proteins become degraded.
Correct Answer:
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Q18: Which of the following mechanisms is used
Q20: The SV40 large T antigen contains all
Q21: The polyomavirus SV40 has been used as
Q22: The large T antigen of SV40 is
Q23: The enhancer sequence on the SV40 chromosome
Q24: SV40 will only transform cells which are
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