Herpes simplex virus (HSV)maintains a latent infection in neurons while Epstein-Barr virus (EBV)maintains latency in B lymphocytes.While EBV maintains a low level of viral DNA replication, HSV does not replicate its genome at all during latency.Which of the following explains this difference?

Question

Quizplus · Accepted Answer

Neurons are a non-dividing cell type while B cells still divide. Since HSV and EBV both maintain a latent infection, the difference in replication activity during latency is likely due to the fact that neurons do not divide whereas B cells do. The lack of DNA replication in neurons may contribute to the maintenance of viral latency.

Herpes Simplex Virus (HSV)maintains a Latent Infection in Neurons While