When it was discovered, what was surprising about the gene that codes for the prion infectious agent?

Question

Quizplus · Accepted Answer

The surprising aspect of the prion infectious agent's gene is that it is found in the genome of the host, meaning it is a normal, functional gene that has undergone a conformational change to become infectious. This was unexpected, as previously, infectious agents were thought to be distinct organisms with their own genetic material.

When It Was Discovered, What Was Surprising About the Gene