The immunologically privileged site that protects the fetus from mother's immune system is most likely due to the fact that _____.
A)mother's IgG do not cross the placenta
B)fetal portion of placenta does not exhibit MHC molecules
C)alpha-fetoprotein inhibits immune responses
D)two of these

Question

Quizplus · Accepted Answer

The fetal portion of the placenta not exhibiting MHC molecules and alpha-fetoprotein inhibiting immune responses both contribute to the immunological privilege that protects the fetus from the mother's immune system. Mother's IgG does cross the placenta, providing passive immunity to the fetus, so A is incorrect.

The Immunologically Privileged Site That Protects the Fetus from Mother's