Because loss-of-function alleles typically do not make a functional gene product,they usually follow the recessive allele inheritance pattern.

Question

Quizplus · Accepted Answer

Loss-of-function alleles result in non-functional proteins, and therefore require both copies of the gene to be affected (homozygous) in order for the phenotype to be expressed. This follows the recessive allele inheritance pattern.

Because Loss-Of-Function Alleles Typically Do Not Make a Functional Gene