What is the purpose of phosphorylating the carboxy terminal domain (CTD)of RNA Polymerase II?
A) convert from the initiation to the elongation stage
B) to aid in transcriptional initiation
C) phosphorylate transcription factors
D) allow transcription factors to bind the TATA box

Question

Quizplus · Accepted Answer

Phosphorylation of the CTD of RNA Polymerase II is required for the transition from transcriptional initiation to the elongation stage. Once the CTD is phosphorylated, RNA Polymerase II is released from the promoter and can begin elongating the transcript.

What Is the Purpose of Phosphorylating the Carboxy Terminal Domain