The scientist(s)________ created a cell-free translation system.An mRNA template was added to a number of tubes,each containing amino acids with a different one radiolabeled.Radiation was measured from the precipitated protein,and this corresponded to the mRNA template that had been added.This was the first experiment that demonstrated the ability to synthesize polypeptides from synthetic mRNA,and revealed a relationship between the two.

Question

The scientist(s)________ created a cell-free translation system.An mRNA template was added to a number of tubes,each containing amino acids with a different one radiolabeled.Radiation was measured from the precipitated protein,and this corresponded to the mRNA template that had been added.This was the first experiment that demonstrated the ability to synthesize polypeptides from synthetic mRNA,and revealed a relationship between the two.

Quizplus · Accepted Answer

The experiment described in the question is the classical experiment conducted by Nirenberg and Matthaei in 1961. They created the first cell-free translation system and demonstrated that polypeptides could be synthesized from synthetic mRNA. They added an mRNA template to a number of tubes, each containing different radiolabeled amino acids, and measured radiation from the precipitated protein. This experiment was critical for understanding the relationship between the nucleotide sequence of mRNA and the amino acid sequence of the polypeptide it encodes.

The Scientist(s)________ Created a Cell-Free Translation System