What kind of mutation would be expected both within oncogenes and tumor suppressor genes that would result in gain-of-function or loss-of-function,respectively?

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Missense mutations are point mutations in which a single nucleotide is changed, leading to a change in the amino acid that is coded for. In oncogenes, missense mutations can result in the production of a gain-of-function protein that is overactive or continuously active, leading to uncontrolled cell growth and division. In tumor suppressor genes, missense mutations can result in a non-functional protein that is unable to suppress cell growth, leading to loss-of-function. Amplifications (B) refer to an increase in the number of copies of a gene, which can also result in overexpression and gain-of-function changes in oncogenes. Silent (C) and neutral (D) mutations do not result in significant changes to protein function.

What Kind of Mutation Would Be Expected Both Within Oncogenes