What does bright orange urine signify in a patient taking rifampicin for treatment of tuberculosis?

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Quizplus · Accepted Answer

Bright orange urine is a common side effect of rifampicin (RMP) therapy. RMP is metabolized by the liver and excreted in the bile, which then enters the intestine and is converted to a bright orange pigment that is eliminated in the urine, hence causing discoloration of the urine. It is not typically associated with urinary tract infections, renal failure, or kidney stones.

What Does Bright Orange Urine Signify in a Patient Taking