What do antipsychotic medications act on to generally moderate spontaneous activity and decrease reactivity to stimuli?

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Antipsychotic medications act on the reticular activating system, which regulates arousal and attention, to generally moderate spontaneous activity and decrease reactivity to stimuli. The hypothalamus and limbic system are involved in regulating emotions and other physiological functions, but are not directly implicated in the action of antipsychotic medications. The cerebellum is not involved in the regulation of arousal or attention, but rather in motor coordination and balance.

What Do Antipsychotic Medications Act on to Generally Moderate Spontaneous