The embryo is most susceptible to damage from substances the mother ingests during the first trimester.

Name: The embryo is most susceptible to damage from substances the mother ingests during the first trimester.
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During the first trimester, the major organs and structures of the embryo are formed, and the developing fetus is most vulnerable to damage from substances such as drugs, alcohol, and certain medications that the mother may ingest.

The Embryo Is Most Susceptible to Damage from Substances the Mother