During presentation of APC-bound antigen,macrophages and dendritic cells secrete the cytokine,________,that activates T helper cells.

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During presentation of APC-bound antigen, macrophages and dendritic cells secrete interleukin-1 (IL-1) cytokine that activates T helper cells. IL-1 acts as a co-stimulatory signal, which is necessary for T cell activation and proliferation. Other cytokines such as interferon and interleukin-2 may also be secreted but they are not the primary signals for T cell activation. Histamine is not a cytokine and does not play a role in antigen presentation or T cell activation.

During Presentation of APC-Bound Antigen,macrophages and Dendritic Cells Secrete the Cytokine,________,that