An RN working in a general medical-surgical unit is caring for a 57-year-old female with a bladder infection. Two weeks prior to hospitalization, the patient was experiencing slight burning upon urination. She self-treated by increasing her intake of fluids, but her symptoms continued to worsen. One week later, she developed generalized abdominal pain and a fever. She presented to the hospital when the pain became unbearable and fever reached 104°F. She was admitted to the medical-surgical unit and started on multiple IV antibiotics with concern that she could be developing a kidney infection.
-Which part of the IgG molecule will bind with the E.coli antigen?

Question

Quizplus · Accepted Answer

The Fab (Fragment antigen-binding) region is the variable region of the immunoglobulin that contains the antigen-binding site, which is specific to the antigen (in this case, E.coli). IgG antibodies are particularly important in defending against bacterial infections, such as bladder or kidney infections caused by E.coli.

An RN Working in a General Medical-Surgical Unit Is Caring