James is no longer able to feel the same effect from his drug of choice with his regular dose;he needs to increase the amount of the drug to feel the desired effect.This demonstrates

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Quizplus · Accepted Answer

Tolerance is the need for higher or more frequent doses of a drug to achieve the same effects that initially occurred with lower doses. Withdrawal refers to the physical and psychological symptoms someone experiences when they stop using a drug, and adjustment and intolerance are not accurate explanations for James' situation.

James Is No Longer Able to Feel the Same Effect