To use a backcross mating strategy for QTL mapping A)two inbred parental strains that differ in a quantitative trait are crossed are mated. B)the F₁ offspring are crossed with each other. C)the F₂ offspring must contain chromosomes that are recombinant betweeen the markers and the genes involved in the trait D)each parent should contain the same alleles at each QTL.

Question

Quizplus · Accepted Answer

In a backcross mating strategy for QTL mapping, two inbred parental strains that differ in a quantitative trait are crossed, and then the offspring are crossed with one of the parental strains to generate a hybrid population. This allows for the comparison of the trait in the hybrid population to the known genotypes of the parental strains. Option B is incorrect because the F₁ offspring are the result of selfing the F₀, which does not help in QTL mapping. Option C is incorrect because while it is true that recombinant chromosomes are desirable for QTL mapping, it is not a requirement for using a backcross mating strategy. Option D is incorrect because if the parents have the same alleles at each QTL, there will be no genetic variation for QTL mapping.

To Use a Backcross Mating Strategy for QTL Mapping